Ketamine
A legal substance used in therapy, intriguing due to its similar effects to psilocybin and MDMA despite being chemically different.
Research
Common Themes
Videos Mentioning Ketamine

The Body Trauma Expert: This Eye Movement Trick Can Fix Your Trauma! The Body Keeps The Score!
The Diary Of A CEO
A legal substance used in therapy, intriguing due to its similar effects to psilocybin and MDMA despite being chemically different.

Freedom, PTSD, war, and life through an evolutionary lens | Sebastian Junger & Peter Attia (Ep. 195)
Peter Attia MD
Discussed as a substance that can be released in the dying brain and cause visions, but not necessarily a near-death experience.

LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Chicago, IL
Andrew Huberman
Mentioned as a drug sometimes lumped with psychedelics, though technically not one, it is discussed in the context of altering neuromodulators.

182 - Psychedelics & Recreational Drugs
Peter Attia MD
A dissociative anesthetic and Schedule III or IV drug, found to have rapid antidepressant effects lasting a few days. It's used for treatment-resistant depression in specialized clinics and through its enantiomer, esketamine (Spravato). However, heavy recreational use can lead to bladder problems and severe cognitive impairment.

Calm App Founder: From $0 To $2 Billion By Making The World Meditate: Michael Acton Smith | E117
The Diary Of A CEO
A dissociative anesthetic being researched for its therapeutic potential in mental health contexts.

#135 - BJ Miller, M.D.: How understanding death leads to a better life
Peter Attia MD
A substance showing new therapeutic values in end-of-life care, related to psychedelics being studied for their impact on anxieties and fears of death.

Jack Kornfield — How to Overcome Apathy and Find Beautiful Purpose
Tim Ferriss
Mentioned as a psychedelic compound with promising therapeutic uses.

Life, Death & the Neuroscience of Your Unique Experience | Dr. David Linden
Andrew Huberman
Mentioned as another therapy used for depression, which also encourages neuroplasticity.

Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast
Andrew Huberman
A compound used clinically for depression, suicidality, and PTSD, but also commonly abused recreationally. It is a dissociative anesthetic.

Q&A with Tim — PR and Marketing Lessons, Time Dilation, Selling to the Affluent, and Much More
Tim Ferriss
A drug whose antidepressant effects were pioneered by Dr. John Crystal; recreational use is associated with bladder damage (ketamine bladder syndrome).

Using Play to Rewire & Improve Your Brain
Andrew Huberman
A neurochemical therapy for severe trauma that is increasingly being paired with talk therapy to explore new ways of thinking and behaving.

The Science of MDMA & Its Therapeutic Uses: Benefits & Risks | Huberman Lab Podcast
Andrew Huberman
A dissociative anesthetic and NMDA receptor blocker, currently legal and used for depression treatment by creating a sense of dissociation from emotions.

#118 – Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging
Peter Attia MD
A drug with interesting antidepressant properties, specifically for recalcitrant depression, and speculated to activate mTOR.

Kelsi Sheren: War, Artillery, PTSD, and Love | Lex Fridman Podcast #230
Lex Fridman
A dissociative anesthetic used for psychedelic-assisted therapy, mentioned as another treatment offered by Heroic Hearts.

The Possibilities of Mind-Altering Compounds | Dr. Suresh Muthukumaraswamy | The Tim Ferriss Show
Tim Ferriss
A dissociative anesthetic and NMDA receptor antagonist used clinically for depression, known for its rapid onset of antidepressant effects compared to SSRIs. It has a complex pharmacology with multiple receptor interactions.

A Billionaire’s Guide To Healing Your Mind And Extending Your Life: Christian Angermayer | E72
The Diary Of A CEO
A psychedelic compound mentioned as one of the many being explored by Atai Life Sciences for mental health issues.

The Science of Psychedelics for Mental Health | Dr. Robin Carhart-Harris
Andrew Huberman
A compound broadly described as psychedelic-like but, in Dr. Carhart-Harris's view, does not capture the world's attention in the same way as classic psychedelics like LSD and psilocybin due to its different primary action.

How Psilocybin Can Rewire Our Brain, Its Therapeutic Benefits & Its Risks
Andrew Huberman
A non-classical psychedelic mentioned for future discussion on the podcast.

The Future of Psychedelic Medicine: A Conversation with Jeannie Fontana and Robin Carhart-Harris
Sam Harris
An existing medicine used for depression, described as a rapid-acting antidepressant but with different properties than classic psychedelics, including potential bladder toxicity and addictive properties.

Andrew Huberman: Sleep, Dreams, Creativity, Fasting, and Neuroplasticity | Lex Fridman Podcast #164
Lex Fridman
A dissociative analgesic being used for trauma therapy to shut off the emotion system from traumatic experiences.

Q&A with Tim Ferriss — Habits, Sleep, Journaling, Psychedelics, HRV Training, and More
Tim Ferriss
Suggested as a potentially legal option for therapeutic use, even in non-psychedelic doses, when other psychedelics are not.

Hamilton Morris on Iboga, 5-MeO-DMT, the Power of Ritual, New Frontiers in Psychedelics, and More
Tim Ferriss
A dissociative anesthetic currently in a 'hype phase' for treatment-resistant depression, but raising concerns about potential urogenital toxicity with widespread use.

Susan Cain on Transforming Pain, Building Your Emotional Resilience, Exploring Sufi Wisdom, and More
Tim Ferriss
A dissociative anesthetic with emerging interest for its effects on neurogenesis and potential in mental health treatment, though with 'not great interest' from Tim Ferriss compared to other compounds.

Erasing Fears & Traumas Based on the Modern Neuroscience of Fear
Andrew Huberman
A dissociative anesthetic used in psychotherapy to create a state of dissociation, allowing individuals to recount traumas without experiencing the usual intense emotional responses. It's being explored for PTSD and depression.