Rapamycin

Jamie Metzl on The Portal (with host Eric Weinstein) Ep. #029 – The Bio-Hacker will see you now

Eric Weinstein

Mentioned as a candidate drug for extending healthspan, part of the longevity interventions Jamie discusses.

357 ‒ A new era of longevity science: models of aging, rapamycin trials, biological clocks, & more

Peter Attia MD

Valter Longo, Ph.D. on Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis

FoundMyFitness

A drug that blocks the mTOR pathway, discussed for its potential anti-aging effects but also associated with negative side effects like hyperglycemia and testicular degeneration.

Supplements for Longevity & Their Efficacy | Dr. Peter Attia

Andrew Huberman

A medication that targets mTOR, taken by Peter Attia for its geroprotective effects, demonstrating life extension in model organisms.

How to Exercise & Eat for Optimal Health & Longevity | Dr. Gabrielle Lyon

Andrew Huberman

A drug that inhibits mTOR, being explored by some as a way to extend lifespan, but poses a contradiction with resistance training which stimulates mTOR.

222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D.

Peter Attia MD

A drug frequently discussed for its potential geroprotective effects, working as an mTOR inhibitor. Its dosing and timing are still complex even in controlled settings.

216 - Metabolomics, NAD+, and cancer metabolism | Josh Rabinowitz, M.D., Ph.D.

Peter Attia MD

A medication Peter Attia takes, acknowledging it has good but imperfect evidence, contrasting with his reluctance to take NAD+ precursors due to lack of compelling human data.