Everolimus
chemical compound
Common Themes
Videos Mentioning Everolimus

175 - The biology of aging, rapamycin, and other interventions that target the aging process
Peter Attia MD
A derivative of rapamycin with the same biochemical mechanism, used in clinical trials to improve vaccine response and immune function in older adults.

171- Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules
Peter Attia MD
A Rapamycin analog that has been tested in humans for enhancing vaccine response to influenza, showing promise at lower doses with fewer side effects.

#123–Joan Mannick & Nir Barzilai: Rapamycin and metformin—longevity, immune enhancement, & COVID-19
Peter Attia MD
A Rapamycin analog (rapalog) used in Joan Mannick's initial trials to enhance immune function in older adults, showing beneficial effects at low, intermittent doses.

#118 – Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging
Peter Attia MD
Also known as avarolamus, a rapamycin analog (rapalog) which was the specific drug used in the 2014 Manick/Klickstein study (referred to as rad001).

Dr. Peter Attia — Longevity Drugs, Alzheimer's Disease, and More
Tim Ferriss
A Rapamycin derivative that, in a 2014 study by Joan Mannick, improved immune response in older adults, challenging the perception of Rapamycin-like drugs as purely immunosuppressive.

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP
Peter Attia MD
A rapalog (Rapamycin analog) used in humans, with studies favoring intermittent dosing strategies to selectively inhibit mTORC1 without long-term mTORC2 inhibition.

#103 – Looking back on the first 99 episodes: Strong Convictions, Loosely Held
Peter Attia MD
A Rapamycin analogue mentioned in the context of a 2014 study that showed augmented vaccination strength in healthy subjects.

#10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — living longer, healthier & turning back the clock
Peter Attia MD
A derivative of rapamycin used in a study on healthy elderly people to test effects on immune function.

Supplements for Longevity & Their Efficacy | Dr. Peter Attia
Andrew Huberman
An analogue of rapamycin, used in a 2014 study by Joan Mannick and Lloyd Klickstein that showed enhanced immunity in 65-year-olds in response to an influenza vaccine.

281 ‒ Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program
Peter Attia MD
Used in humans to improve vaccine responses to influenza vaccination in some circumstances.