Canagliflozin
A SGLT2 inhibitor drug that has succeeded in the ITP.
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Videos Mentioning Canagliflozin
171- Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules
Peter Attia MD
An SGLT2 inhibitor tested in the ITP, suggesting its benefits on longevity might be related to glucose kinetics rather than caloric intake.
Journal Club with Dr. Peter Attia | Metformin for Longevity & The Power of Belief Effects
Andrew Huberman
An SGLT2 inhibitor that was very successful in the ITP, showing a survival benefit in mice not through calorie restriction but likely through lower glucose and insulin.
Dr. Peter Attia — Longevity Drugs, Alzheimer's Disease, and More
Tim Ferriss
An SGLT2 inhibitor that works in the kidney to block glucose reuptake, leading to glucose excretion. A successful drug for type 2 diabetes, heart failure, and mortality, also extended lifespan in mice in the ITP.
#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP
Peter Attia MD
An SGLT2 inhibitor used for diabetes that blocks peak glucose in mice and humans, extending lifespan preferentially in male mice, with mechanisms potentially beyond direct glucose control.
![Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent [AMA 45 sneak peek]](https://i.ytimg.com/vi/GCCHOBLTiCk/maxresdefault.jpg)
Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent [AMA 45 sneak peek]
Peter Attia MD
A specific SGLT2 inhibitor mentioned for its promising geroprotective effects.
300-Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, & more
Peter Attia MD
A SGLT2 inhibitor drug that has succeeded in the ITP.
Supplements for Longevity & Their Efficacy | Dr. Peter Attia
Andrew Huberman
An SGLT2 inhibitor that showed success in the Interventions Testing Program (ITP) for life extension.