Alzheimer's disease

This Supplement Could Cut Your Dementia Risk By 40%

FoundMyFitness

A neurodegenerative disease linked to APOE4 and amyloid beta pathology, where Vitamin D supplementation has shown potential benefits in reducing risk and progression.

#48–Matt Walker, Ph.D., on Sleep (Part 2 of 3): Heart disease, cancer, causes of sleep disruption...

Peter Attia MD

Neurodegenerative disease discussed in relation to sleep deprivation, growth hormone, IGF, and genetic predispositions like APOE4. It is strongly linked to lack of sleep.

LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Chicago, IL

Andrew Huberman

A neurodegenerative disorder discussed in relation to the potential neuroprotective effects of nicotine.

#138-Lauren Rogen & Richard Isaacson MD: Alzheimer’s disease prevention—patient & doctor perspective

Peter Attia MD

The primary subject of the podcast, discussed from personal and scientific perspectives, focusing on prevention and pathology.

All Things Sleep (Weight Gain, Alzheimer’s Disease, Caffeine, and More) — Dr. Matthew Walker

Tim Ferriss

A form of dementia typified by memory impairment and decline, linked to the buildup of beta-amyloid and Tau proteins in the brain. Sleep plays a critical role in its prevention.

#47–Matt Walker, Ph.D. on Sleep (Part 1 of 3): Dangers of poor sleep, dementia risk, mental health..

Peter Attia MD

A form of dementia that Matthew Walker's research focuses on, with strong causal evidence linking it to insufficient sleep.

175 - The biology of aging, rapamycin, and other interventions that target the aging process

Peter Attia MD

An age-related neurodegenerative disease, mentioned as one of the major causes of death and disability where biological age is a significant risk factor, and its relationship to aging biology is explored.

171- Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules

Peter Attia MD

A neurodegenerative disease, noted as the only major cause of death where women do not die at a lower rate than men, leading to a hypothesis about an autoimmune component.

#123–Joan Mannick & Nir Barzilai: Rapamycin and metformin—longevity, immune enhancement, & COVID-19

Peter Attia MD

A neurodegenerative disease impacting memory and cognition, linked to protein aggregation, and a potential target for Metformin and rapalogs.

166 - Oral health, best hygiene practices, & relationship between oral health and systemic disease

Peter Attia MD

A neurodegenerative disease linked to periodontal disease through associations, with research showing markers of Alzheimer's and amyloid accumulation in children with Down Syndrome and poor oral health.

John Abramson: Big Pharma | Lex Fridman Podcast #263

Lex Fridman

A neurodegenerative disease, the target of Aduhelm, where reducing amyloid plaques was not shown to correlate with clinical progression.

#159-Peter Hotez MD, PhD.: The anti-vaccine movement, causes of autism, & COVID-19 vaccine update

Peter Attia MD

A neurodegenerative disease discussed in the context of increasing prevalence due to longer lifespans, improved diagnosis, and potential environmental factors like metabolic disease and fungal involvement.

How Smells Influence Our Hormones, Health & Behavior | Dr. Noam Sobel

Andrew Huberman

A neurodegenerative disease for which loss of smell is an early sign, potentially linked to pathogens entering the brain through the olfactory system.

#114 – Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies

Peter Attia MD

Autophagy plays a crucial role in preventing neurodegeneration, with evidence suggesting that defects in autophagy can lead to Alzheimer's-like pathology.

World No.1 Fasting Expert: The Link Between Cancer & Fasting That They're Hiding From You!

The Diary Of A CEO

Cognitive Decline Expert: The Disease That Starts in Your 30s but Kills You in Your 70s

The Diary Of A CEO

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP

Peter Attia MD

A neurodegenerative disease that does not ordinarily occur in mice but can be studied in engineered mouse models, where anti-aging drugs have shown postponement of the disease.

#147-Hussein Yassine, M.D.: Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s

Peter Attia MD

A neurodegenerative disease characterized by amyloid accumulation, tau tangles, cognitive decline, and loss of daily function, strongly linked to APOE4.

The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Andrew Huberman

A neurodegenerative disease that some associate with long-term statin use.

#35 – Nir Barzilai, M.D.: How to tame aging

Peter Attia MD

A neurodegenerative disease for which Metformin has shown some positive effects in mild cognitive impairment in clinical studies, particularly in memory recall.

#38–Francisco Gonzalez-Lima, Ph.D.: Alzheimer’s disease & the vascular hypothesis

Peter Attia MD

A neurodegenerative disease that is the topic of this episode, with a focus on its vascular hypothesis.

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray

Andrew Huberman

A neurodegenerative disease discussed in the context of blood signatures and potential treatments.

#23–Tom Dayspring Part IV of V: statins, Zetia, PCSK9 inhibitors, niacin, cholesterol & the brain

Peter Attia MD

A multifactorial disease that can be influenced by metabolic and vascular components. The hypothesis is that while statins might reduce vascular components in some, over-suppression of cholesterol synthesis in the brain could increase susceptibility in others.

Daphne Koller: Biomedicine and Machine Learning | Lex Fridman Podcast #93

Lex Fridman

A neurodegenerative disease discussed as being poorly understood, with current hypotheses not yet sufficiently validated.