Nicotinamide Riboside
chemical compound
Common Themes
Videos Mentioning Nicotinamide Riboside

175 - The biology of aging, rapamycin, and other interventions that target the aging process
Peter Attia MD
An NAD+ precursor or booster, one of two widely discussed forms used in studies of healthy aging. Efficacy and biological availability are subjects of debate and inconsistent reproducibility.

#46–Chris Masterjohn, Ph.D.: Pathways to health and disease (NAD, sirtuins, methylation, choline...
Peter Attia MD
An NAD+ precursor supplemented orally to increase NAD+ levels, believed to be more effective than nicotinamide for increasing hepatic NAD+ due to its metabolism pathway.

The Life-Extension Episode With Dr. Matt Kaeberlein | The Tim Ferriss Show
Tim Ferriss
An NAD+ precursor whose stability and bioavailability are debated, and whose lifespan-extending effects in mice have not been consistently reproduced by the ITP.

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP
Peter Attia MD
A popular NAD+ precursor supplement tested in the ITP, which did not extend lifespan in mice at the tested dose, and did not consistently show increased NAD+ levels in tissues.

#35 – Nir Barzilai, M.D.: How to tame aging
Peter Attia MD
A precursor to NAD+, discussed alongside NMN for its potential anti-aging effects, with questions about its bioavailability and clinical efficacy.

#27 – David Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of aging
Peter Attia MD
NR is a one-step precursor to NAD+ and is packaged with pterostilbene in some over-the-counter products, shown to raise NAD+ levels in the body and cells.

#70–David Sinclair, PhD: How cellular reprogramming could slow our aging clock, & the latest on NAD
Peter Attia MD
A precursor to NAD+, chemically similar to DNA and Vitamin B3, directly absorbed by cells and converted to NMN, then NAD+, making it a promising booster.

#02 – Rhonda Patrick, Ph.D.: paradox of IGF-1, ketogenic diets and genetics, benefits of sauna, NAD+
Peter Attia MD
A precursor to NAD+, discussed as a supplement that can increase NAD+ levels in plasma and improve mitochondrial function in animal models.

Dr. Mark Mattson on the Benefits of Stress, Metabolic Switching, Fasting, and Hormesis
FoundMyFitness
A compound mentioned as a 'fasting mimetic' but for which there is insufficient data to support its use.

Supplements for Longevity & Their Efficacy | Dr. Peter Attia
Andrew Huberman
A precursor to NAD+, discussed alongside NMN and direct NAD+ infusions for increasing NAD+ levels.

216 - Metabolomics, NAD+, and cancer metabolism | Josh Rabinowitz, M.D., Ph.D.
Peter Attia MD
An oral NAD+ precursor that gets broken down in the GI tract, mainly entering the body as nicotinic acid (niacin). It's considered a niacin prodrug.

201 - Deep dive back into Zone 2 Training | Iñigo San-Millán, Ph.D. & Peter Attia, M.D.
Peter Attia MD
A precursor to NAD+, discussed as a longevity-boosting supplement, but with theoretical risks related to potentially favoring tumor metabolism, based on pilot studies in mice.

Dr. Rhonda Patrick Returns | The Tim Ferriss Show (Podcast)
Tim Ferriss
A form of Vitamin B3 converted into NAD+, with animal studies showing improved mitochondrial function, biogenesis, muscle mass, and metabolism. Human studies are ongoing for optimal dosing.

Dr David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!
The Diary Of A CEO
Another precursor to NAD+, mentioned as an alternative to NMN.