autophagy
cellular catabolic process in which cells digest parts of their own cytoplasm
Common Themes
Videos Mentioning autophagy
Insulin Doctor: The Fastest Way To Burn Dangerous Visceral Fat! I'm Finding Mould In My Patients!
The Diary Of A CEO
A cellular process where the cell recycles redundant organelles and components, improving efficiency and removing toxins.
#123–Joan Mannick & Nir Barzilai: Rapamycin and metformin—longevity, immune enhancement, & COVID-19
Peter Attia MD
A cellular process of self-degradation and recycling components, which can be affected by mTOR inhibitors; its induction varies by cell type with rapalogs.
The Biology of Slowing & Reversing Aging | Dr. David Sinclair
Andrew Huberman
A cellular cleansing system that digests old and misfolded proteins, activated during hunger, with deeper forms kicking in after 2-3 days of fasting.
#35 – Nir Barzilai, M.D.: How to tame aging
Peter Attia MD
A cellular process of self-degradation and recycling, increased by Metformin, which is important for longevity and improved by fasting in rodents.
#31 – Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease
Peter Attia MD
A cellular process promoted by AMPK activation, important for cellular cleanup.
Results from Peter's 3 week "nothingburger" (1 week keto—1 week fast—1 week keto) (AMA #2)
Peter Attia MD
Speculated as a potential reason, alongside DNA turnover, for the uric acid spike after fasting, though not explicitly confirmed.
#01 – Tim Ferriss: depression, psychedelics, and emotional resilience
Peter Attia MD
The cellular process of recycling old and damaged cell parts, induced by fasting.
Dr. Rhonda Patrick Returns | The Tim Ferriss Show (Podcast)
Tim Ferriss
A genetic program activated by prolonged fasting (4-5 days in humans) that clears away damaged cells and cellular components for energy, preventing them from becoming cancer or senescent cells.
Dr. Arthur De Vany Interview | The Tim Ferriss Show (Podcast)
Tim Ferriss
The process of consuming self-tissues, used in immune function and stem cell maintenance, peaking 4-6 hours post-exercise.
Dr. Dominic D'Agostino on Fasting, Ketosis, and The End of Cancer
Tim Ferriss
A cellular process of self-eating and waste removal, which therapeutic fasting can trigger, potentially purging precancerous cells.