Alpha-GPC
Choline-containing nootropic discussed as a potential cognitive enhancer.
Common Themes
Videos Mentioning Alpha-GPC

ADHD & How Anyone Can Improve Their Focus
Andrew Huberman
Choline-containing nootropic discussed as a potential cognitive enhancer.

Mental Health Toolkit: Tools to Bolster Your Mood & Mental Health
Andrew Huberman
Often combined with L-Tyrosine, used to enhance dopamine and acetylcholine levels for mental health improvement.

The Science of Love, Desire and Attachment
Andrew Huberman
An ingredient used in Thesis nootropics, personally used by the host.

Leverage Dopamine to Overcome Procrastination & Optimize Effort
Andrew Huberman
A supplement Andrew Huberman takes occasionally before resistance workouts to enhance focus and performance.

Science of Mindsets for Health & Performance | Dr. Alia Crum
Andrew Huberman
An ingredient Andrew Huberman particularly likes and is included in his customized Thesis formulations.

The Science of Making & Breaking Habits
Andrew Huberman
A supplement mentioned as a way to elevate dopamine and norepinephrine levels, useful in phase one of the day for overcoming limbic friction.

Developing a Rational Approach to Supplementation for Health & Performance | Huberman Lab Podcast
Andrew Huberman
A choline donor that enhances focus by augmenting acetylcholine pathways, providing heightened focus without the jittery feeling of stimulants.

The Science of Creativity & How to Enhance Creative Innovation
Andrew Huberman
A supplement that Andrew Huberman sometimes combines with L-Tyrosine to enhance dopamine levels.

Nutrients For Brain Health & Performance | Huberman Lab Podcast #42
Andrew Huberman
A compound in the acetylcholine biosynthesis pathway that Andrew Huberman takes 2-3 times per week at 300 milligrams to enhance choline function, noting high dosages for cognitive decline studies.

Science-Based Tools for Increasing Happiness
Andrew Huberman
An ingredient used in Thesis nootropics, mentioned as a high-quality ingredient discussed on the podcast.

Maximizing Productivity, Physical & Mental Health with Daily Tools
Andrew Huberman
A non-stimulant supplement that supports the release of acetylcholine, enhancing physical and cognitive performance, with recommended dosages around 300mg.

Focus Toolkit: Tools to Improve Your Focus & Concentration
Andrew Huberman
A nootropic ingredient used by Thesis and discussed as a supplement to acutely increase acetylcholine, taken at 300-600mg before intense cognitive or physical work.

Exercise, Nutrition, Hormones for Vitality & Longevity | Dr. Peter Attia
Andrew Huberman
A cholinergic compound taken before cognitive work or workouts to enhance focus, with subjective benefits.

Optimize & Control Your Brain Chemistry to Improve Health & Performance | Huberman Lab Podcast #80
Andrew Huberman
A compound in the choline pathway that increases acetylcholine synthesis, enhancing focus. Often taken with caffeine and phenylethylamine.

Supplements for Longevity & Their Efficacy | Dr. Peter Attia
Andrew Huberman
A supplement some people take (600-900mg) with coffee before a workout for a stimulant effect, but it can increase TMAO.

Understand & Improve Memory Using Science-Based Tools
Andrew Huberman
A nootropic ingredient used in Thesis blends and discussed as a compound that can increase epinephrine and adrenaline, potentially enhancing memory.

How to Learn Skills Faster
Andrew Huberman
A supplement sold over-the-counter that can enhance power output, improve cognitive function (especially in older populations and those with neurodegeneration like Alzheimer's), increase fat oxidation, and promote growth hormone release to a small degree.

Dr. Andrew Huberman — A Neurobiologist on Sleep, Performance, and Anxiety | The Tim Ferriss Show
Tim Ferriss
A nootropic supplement thought to enhance cognitive function, used by Huberman for focus without excessive arousal.

How to Focus to Change Your Brain
Andrew Huberman
A supplement that can increase cholinergic transmission in the brain.

Using Science to Optimize Sleep, Learning & Metabolism
Andrew Huberman
A compound that some evidence suggests can increase acetylcholine, a neurotransmitter important for focus and learning.

257 ‒ Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies
Peter Attia MD
Another form of choline mentioned as being less studied in the context of traumatic brain injury compared to citicoline.

Dr. Matt Walker: Protocols to Improve Your Sleep | Huberman Lab Guest Series
Andrew Huberman
An over-the-counter supplement that acts as a precursor to acetylcholine, discussed in the context of its potential yet tricky role in sleep augmentation.

Dr. Rhonda Patrick Returns | The Tim Ferriss Show (Podcast)
Tim Ferriss
A naturally occurring form of choline believed to cross the blood-brain barrier quickly. Studies suggest it can enhance cognitive performance and prevent mental exhaustion after intense exercise.

Dr. Andy Galpin: Optimal Nutrition & Supplementation for Fitness | Huberman Lab Guest Series
Andrew Huberman
A non-stimulant cholinergic agonist that promotes focus and alertness. Typically used at 300-600mg prior to hard physical or mental training, but not recommended for daily use to avoid over-arousal.