Modafinil

Balaji Srinivasan — How to Start a New Country

Tim Ferriss

Nootropic mentioned as an example of a performance enhancer for cognition that can be spotted in the 'funnel' of racehorses, patients with wasting diseases, bodybuilders, and professional athletes.

All Things Sleep (Weight Gain, Alzheimer’s Disease, Caffeine, and More) — Dr. Matthew Walker

Tim Ferriss

A wake-promoting chemical prescribed for narcolepsy, also used off-label as a performance enhancer. Its exact mechanism is unclear, potentially involving noradrenaline, serotonin, and histamine. Can lead to rapid tolerance and productivity annihilation upon cessation.

Adderall, Stimulants & Modafinil for ADHD: Short- & Long-Term Effects

Andrew Huberman

A non-stimulant prescription drug that improves ADHD symptoms and is also used for daytime sleepiness, with a longer duration of action and a different mechanism than amphetamines.

Neuralink & Technologies to Enhance Human Brains | Dr. Matthew MacDougall

Andrew Huberman

A wakefulness-promoting drug, discussed for its widespread use, potential benefits in prescribed amounts, and unknown chronic effects outside of addiction.

Leverage Dopamine to Overcome Procrastination & Optimize Effort

Andrew Huberman

A legal prescription drug that taps into the dopamine system to significantly increase baseline levels of dopamine for many hours, used for increasing motivation and attention.

The Science of Creativity & How to Enhance Creative Innovation

Andrew Huberman

A prescription drug that increases dopamine and focus and is sometimes used to stay awake, with potential side effects.

Using Caffeine to Optimize Mental & Physical Performance

Andrew Huberman

A prescription drug that is potent for ADHD treatment.

Master Your Sleep & Be More Alert When Awake | Huberman Lab Essentials

Andrew Huberman

A prescription stimulant designed for the treatment of narcolepsy to create wakefulness.

How to Improve at Learning Using Neuroscience & AI | Dr. Terry Sejnowski

Andrew Huberman

A nootropic mentioned as a substance people take to enhance cognitive function, beyond its use for narcolepsy.

Nicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping

Andrew Huberman

A prescription compound that can be used to enhance focus.

#17 – Mike Trevino: life-lessons from ultra-endurance, mindset, hard work, and removing limitations

Peter Attia MD

A non-stimulant drug approved for narcolepsy, used by Peter Atia during residency to stay awake, and mentioned as a potentially useful drug for military special forces.

Focus Toolkit: Tools to Improve Your Focus & Concentration

Andrew Huberman

A prescription drug used for narcolepsy that increases dopamine and epinephrine transmission, thereby enhancing focus and concentration; its use without prescription is discouraged.

LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Seattle, WA

Andrew Huberman

A wakefulness-promoting drug mentioned in the context of ADHD medications and their widespread use.

Optimize & Control Your Brain Chemistry to Improve Health & Performance | Huberman Lab Podcast #80

Andrew Huberman

A prescription drug with increasing interest in use, covered in the ADHD episode, that can increase dopamine.

Therapy, Treating Trauma & Other Life Challenges | Dr. Paul Conti

Andrew Huberman

A stimulant medication mentioned in the context of improving focus.

Boost Attention & Memory with Science-Based Tools | Dr. Wendy Suzuki

Andrew Huberman

A prescription medication used to treat sleep disorders, also used off-label by college students for cognitive enhancement.

Understand & Improve Memory Using Science-Based Tools

Andrew Huberman

A prescription drug, mentioned as a stimulant that some individuals are prescribed to increase alertness and focus, but generally cautioned against for non-prescribed use due to addictive potential.

Dr. Peter Attia, MD — Fasting, Metformin, Athletic Performance, and More | The Tim Ferriss Show

Tim Ferriss

A potent nootropic Peter Attia acknowledges but emphasizes that proper nutrition, exercise, and sleep are superior nootropics.

Using Science to Optimize Sleep, Learning & Metabolism

Andrew Huberman

A stimulant drug originally designed for narcolepsy treatment, known to improve learning and memory, but is expensive.

LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Melbourne, AU

Andrew Huberman

Mentioned as a substance some older individuals are starting to take for cognitive enhancement.

So I Tried Ketamine… | Bryan Johnson Podcast

Bryan Johnson

Discussed in contrast to cocaine; its mechanism for keeping people awake is not classically stimulant-like and differs from cocaine's action.

ADHD & How Anyone Can Improve Their Focus | Huberman Lab Essentials

Andrew Huberman

The Hidden Risks of Meditation — Dr. Willoughby Britton | The Tim Ferriss Show

Tim Ferriss

A stimulant drug mentioned as a parallel to meditation's attention-enhancing effects, with potential for hyperarousal syndrome at higher doses.

How to Improve Oral Health & Its Critical Role in Brain & Body Health

Andrew Huberman

A medication that qualifies as a stimulant, potentially making saliva more acidic and negatively impacting oral health.