Spermidine
A robust molecule that extended lifespan and restored metabolism in mice, even in a calorie-challenged context. Optimistic about its potential.
Videos Mentioning Spermidine

#114 – Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies
Peter Attia MD
Mentioned as a pharmacologic agent that is a potent stimulator of autophagy, explored for healthy individuals as a 'Fountain of Youth' type pill.

The Life-Extension Episode With Dr. Matt Kaeberlein | The Tim Ferriss Show
Tim Ferriss
A natural product found in food, thought to enhance autophagy and shown to extend lifespan in some organisms and improve healthspan measures in mice. It's considered an autophagy booster.

357 ‒ A new era of longevity science: models of aging, rapamycin trials, biological clocks, & more
Peter Attia MD
A robust molecule that extended lifespan and restored metabolism in mice, even in a calorie-challenged context. Optimistic about its potential.

Valter Longo, Ph.D. on Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis
FoundMyFitness
A compound considered a fasting-mimicking drug that activates signaling pathways similar to fasting.

Dr David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!
The Diary Of A CEO
A naturally occurring polyamine that Dr. Sinclair takes; it extends the lifespan of various animals and appears to stimulate autophagy and delay epigenetic information loss.