reactive oxygen species

Q&A on Zone 2 Exercise with Peter Attia, M.D.

Peter Attia MD

Damage caused by these species can be combated by improved mitochondrial function, a benefit of Zone 2 training.

#31 – Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease

Peter Attia MD

Molecules like superoxide and hydrogen peroxide which can be toxic but also beneficial as signaling molecules in mitochondria.

#66 – Vamsi Mootha, MD: Aging, T2D, cancer, dementia, Parkinson’s—do all roads lead to mitochondria?

Peter Attia MD

Typically viewed negatively, but also important signaling molecules that play a role in adaptation to exercise and selective targeting of cancer cells.

#14 – Robert Lustig, M.D., M.S.L.: fructose, processed food, NAFLD, and changing the food system

Peter Attia MD

Unstable molecules that can cause cellular damage, produced during the Maillard reaction, which fructose accelerates.

Using Light (Sunlight, Blue Light & Red Light) to Optimize Health

Andrew Huberman

Byproducts of cellular energy production that accumulate with age, causing cellular damage; red light therapy can reduce ROS by activating mitochondria.

Gordon Lithgow, Ph.D. on Protein Aggregation, Iron Overload & the Search for Longevity Compounds

FoundMyFitness

Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation

FoundMyFitness

Byproducts of mitochondrial dysfunction that can cause cellular damage and are increased when mitophagy is inhibited.

Supplements for Longevity & Their Efficacy | Dr. Peter Attia

Andrew Huberman

Molecules that can impede mitochondrial function, targeted by some anti-aging approaches like red light therapy.