Tylenol

How To Increase Your Testosterone Levels Naturally | Derek from MPMD

FoundMyFitness

Mentioned as an example of a common drug to which some people can have extreme individual responses, illustrating the variability in drug side effects.

How to Understand Emotions | Dr. Lisa Feldman Barrett

Andrew Huberman

An over-the-counter painkiller that, along with Ibuprofen, is shown to reduce negative feelings.

Efforts & Challenges in Promoting Public Health | Dr. Vivek Murthy

Andrew Huberman

A common medication generally considered safe, but with a known rate of rare side effects such as liver damage, which is important context for understanding vaccine adverse effects.

Dr. Gina Poe: Use Sleep to Enhance Learning, Memory & Emotional State | Huberman Lab Podcast

Andrew Huberman

An over-the-counter pain medication mentioned as an alternative to opiates for pain management.

Jamie Metzl: Lab Leak Theory | Lex Fridman Podcast #247

Lex Fridman

An over-the-counter pain reliever, used as an example to discuss the risk-benefit calculations in public health and regulation.

#155 - Chris Sonnenday, M.D.: The history, challenges, and gift of organ transplantation

Peter Attia MD

A common over-the-counter painkiller with a dangerously low lethal dose (LD50), making it a frequent cause of acute liver failure through overdose, either accidental or intentional.

#28–Mark & Chris Bell: steroids, powerlifting, addiction, diet, training, & helping others live well

Peter Attia MD

A common over-the-counter pain reliever that Peter Attia controversially claims is less safe than anabolic steroids used at physiological levels, highlighting his belief in the relative safety of medically supervised testosterone replacement.

Understanding & Conquering Depression

Andrew Huberman

A pain reliever, mentioned as an example of a painkiller that can help with emotional pain, though not a recommendation for that purpose.

#12 – Corey McCarthy: Overcoming trauma, finding meaning, changing the self-narrative, & gratitude

Peter Attia MD

An over-the-counter pain medication that Corey ingested in a lethal dose during a suicide attempt at age 13, leading to hospitalization and near-liver failure.

Doping, Collagen, Goals, and Hyperplasia (Episode 33)

Stronger By Science

A common pain reliever, used in a hypothetical example to emphasize the importance of dosage disclosure in research.

Dr. Peter Attia, MD — Fasting, Metformin, Athletic Performance, and More | The Tim Ferriss Show

Tim Ferriss

Used as an analogy to illustrate the problem of not knowing the correct dosage for beneficial interventions like fasting.

E40: A Bestie gets COVID, Delta breakthrough, Billionaire Space Race & more

All-In Podcast

Medication taken by David Sachs to control his fever during his COVID-19 infection.

H-1B Shakeup, Kimmel Apology, Autism Causes, California Hate Speech Law

All-In Podcast

Create Your Ideal Future Using Science-Based Protocols | Ari Wallach

Andrew Huberman

Over-the-counter pain reliever that a study showed could alleviate emotional pain after a breakup, indicating a shared neural circuitry for physical and emotional pain.

Advil, Aspirin, and Tylenol -- What's the difference?

Sabine Hossenfelder

The brand name for acetaminophen in the United States, a widely used pain reliever known for being easier on the digestive system but with a narrow therapeutic window.

202 - Peter on nutrition, disease prevention, and more — looking back on the last 100 episodes

Peter Attia MD

Used as an example to critique the legal removal of Phenibut; Peter argues that Tylenol, despite being lethal in overdose, remains legal, highlighting an inconsistency in regulatory decisions.

Tools to Reduce & Manage Pain | Dr. Sean Mackey

Andrew Huberman

A brand name for acetaminophen, which has a slightly different, more centrally acting mechanism for pain relief and is safer on the stomach than NSAIDs but can be harmful to the liver in high doses.

Jonathan Reisman: The Human Body - From Sex & Sperm to Hands & Heart | Lex Fridman Podcast #297

Lex Fridman

Common painkiller mentioned as being toxic to the liver in overdose, due to the liver's role in metabolizing drugs.

Erik Vance (Full Episode) | The Tim Ferriss Show (Podcast)

Tim Ferriss

A common over-the-counter pain reliever, used as an example to illustrate how people can experience a placebo effect before the active drug takes effect.

Dom D'Agostino Returns (Full Episode) | The Tim Ferriss Show (Podcast)

Tim Ferriss

Mentioned as an example of common substances that can be toxic in high amounts.

Mike Birbiglia Interview (Full Episode) | The Tim Ferriss Show (Podcast)

Tim Ferriss

Over-the-counter pain reliever, used in an analogy to explain that things in excess can become harmful.

220 ‒ Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D.

Peter Attia MD

A common pain reliever mentioned as an example of a drug that can poison the liver at a certain dose, unlike LSD which has no LD50.

This Isn’t the Trump You Remember. The SURPRISING U-Turn You Didn't See Coming | Tom Bilyeu Show

Tom Bilyeu

Acetaminophen, discussed in relation to potential links with autism and hyperactivity in children when used by pregnant women. The company's own recommendation against use during pregnancy is noted.