Naltrexone
An opioid receptor blocker used to treat alcohol use disorder by making alcohol less reinforcing, and also for opioid addiction.
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Videos Mentioning Naltrexone

How to Breathe Correctly for Optimal Health, Mood, Learning & Performance
Andrew Huberman
A medication mentioned as potentially blocking opioid receptors in the Pre-Bötzinger Complex to prevent death from opioid overdose.

Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast
Andrew Huberman
A drug used to block the opioid receptor pathway, which when administered with ketamine, prevents ketamine's antidepressant effects, suggesting opioid system involvement.

Control Stress for Healthy Eating, Metabolism & Aging | Dr. Elissa Epel
Andrew Huberman
An opioid receptor blocker, discussed in its potential use in combination with Wellbutrin to reduce compulsive eating for binge eating disorder.

How to Control Your Sense of Pain & Pleasure
Andrew Huberman
A prescription drug typically used for opioid addiction, but found in low doses (1/10th typical) to be successful in treating certain forms of fibromyalgia by blocking toll-4 receptors on glial cells.

Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams
Andrew Huberman
A mu and kappa opiate receptor antagonist used in a study to block the antidepressant effect of ketamine, revealing the opioid system's role in ketamine's efficacy.

321 – Dopamine and addiction: navigating pleasure, pain, and the path to recovery
Peter Attia MD
An opioid receptor blocker used to treat alcohol use disorder by making alcohol less reinforcing, and also for opioid addiction.