Mdm2

Concept

A ubiquitin ligase that marks proteins, including p53, for destruction. Inhibiting Mdm2-p53 interaction can selectively kill senescent cells.

Mentioned in 1 video

Videos Mentioning Mdm2

#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it

#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it

Peter Attia MD

A ubiquitin ligase that marks proteins, including p53, for destruction. Inhibiting Mdm2-p53 interaction can selectively kill senescent cells.