TNF-alpha
A cytokine involved in systemic inflammation, identified by Dr. Kevin Tracy in the context of septic shock.
Common Themes
Videos Mentioning TNF-alpha
#140 - Gerald Shulman, MD, PhD: Insulin resistance—molecular mechanisms and clinical implications
Peter Attia MD
An inflammatory cytokine mentioned as being released by macrophages (crown-like structures) in fat cells, promoting increased lipolysis and contributing to fasting hyperglycemia.
#134 - James O’Keefe, M.D.: Preventing cardiovascular disease and the risk of too much exercise
Peter Attia MD
A master hormone of inflammation; its inhibition is being studied for dementia prevention, with biologics and natural compounds like curcumin showing promise.
#123–Joan Mannick & Nir Barzilai: Rapamycin and metformin—longevity, immune enhancement, & COVID-19
Peter Attia MD
A pro-inflammatory cytokine. Studies on Metformin and COVID-19 showed a significant decrease in plasma TNF-alpha levels, suggesting an anti-inflammatory effect.
#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it
Peter Attia MD
A pro-inflammatory SASP factor that is the target of successful drugs like Humira, indicating its role in bad biology.
How Foods and Nutrients Control Our Moods
Andrew Huberman
An inflammatory cytokine whose elevated levels can indicate inflammation and are reduced by a higher omega-3 to omega-6 ratio.
Dr. Michael Levin — Reprogramming Bioelectricity
Tim Ferriss
A cytokine involved in systemic inflammation, identified by Dr. Kevin Tracy in the context of septic shock.
The Random Show, Couch Edition! — Supplements, Breathing and Balance Training, and Much More!
Tim Ferriss
A cytokine involved in systemic inflammation, whose modulation is connected to vagus nerve stimulation research.