p53
A protein whose mutation is linked to half of human tumors, and which relies on zinc fingers for function.
Videos Mentioning p53
#114 – Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies
Peter Attia MD
A tumor suppressor protein and transcription factor, p53 promotes apoptosis by activating proteins like Puma and Nox, which antagonize bcl-2. Loss of p53 function accounts for about half of all cancers.
#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it
Peter Attia MD
A tumor suppressor protein whose concentration increases in senescent cells when its interaction with Mdm2 is inhibited, leading to selective cell death.
Using Light (Sunlight, Blue Light & Red Light) to Optimize Health
Andrew Huberman
A protein involved in cell maturation and function, upregulated by UVB light exposure to the skin, which is required for downstream increases in sex hormones and gonadal size.
CHORIBar: Micronutrients, Fiber & Polyphenols in a Bar
FoundMyFitness
A protein whose mutation is linked to half of human tumors, and which relies on zinc fingers for function.
213 ‒ Liquid biopsies and cancer detection | Max Diehn, M.D. Ph.D.
Peter Attia MD
A tumor suppressor gene, often mutated in various cancers, but not always a 'driver' mutation.