C. Elegans
species of fungus
Common Themes
Videos Mentioning C. Elegans

#41–Jake Kushner, M.D.: How to thrive with T1D and the valuable insights that can benefit anyone
Peter Attia MD
A nematode worm used as a model organism in genetic and aging research, notably in studies by Dr. Cynthia Kenyon on insulin signaling and lifespan.

#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it
Peter Attia MD
A millimeter-sized worm used in Cynthia Kenyon's groundbreaking research where knockdown of a single gene doubled its lifespan.

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP
Peter Attia MD
A nematode worm, commonly used model organism in aging research, where Daf mutants were first shown to extend lifespan.

Understanding & Treating Addiction | Dr. Anna Lembke
Andrew Huberman
A primitive worm mentioned as an example of organisms that release dopamine when food is sensed in the environment.

Elizabeth Iorns on Biotech Companies in YC
Y Combinator
A model organism (nematode worm) used in research to study aging and longevity, although its results may not always translate directly to humans.

#02 – Rhonda Patrick, Ph.D.: paradox of IGF-1, ketogenic diets and genetics, benefits of sauna, NAD+
Peter Attia MD
A transparent nematode (worm) used as a model organism in longevity research, particularly in studies on IGF-1 and daf-16 mutants.

Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots | Lex Fridman Podcast #325
Lex Fridman
A nematode (roundworm) model organism where every cell is 'numbered' and has a fixed developmental fate, contrasting with the high plasticity found in most other organisms.

252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting
Peter Attia MD
A worm often studied in longevity research (daf-16/daf-2 mutation, igf-1 pathway), but whose findings may not directly translate to humans due to significant biological differences.

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.
Peter Attia MD
A nematode, one of the simplest organisms where changing a single gene (like the insulin receptor) can lead to significantly extended lifespan, serving as an initial inspiration for longevity research.

#60 – Annie Duke: How to improve decision making, learning, & apply ‘backcasting’ for future success
Peter Attia MD
A nematode worm often used as a model organism in biological research due to its simplicity and ease of study, compared to poker as a model system for decision-making.