Daf-2
ConceptMentioned in 2 videos
A gene mutation in C. elegans, an analog of the IGF-1 receptor, shown to extend lifespan, a foundational discovery in aging.
Videos Mentioning Daf-2

#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it
Peter Attia MD
A gene discovered in Cynthia Kenyon's screen, associated with the IGF-1 receptor signaling pathway, manipulated to extend lifespan in C. elegans.

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP
Peter Attia MD
A gene mutation in C. elegans, an analog of the IGF-1 receptor, shown to extend lifespan, a foundational discovery in aging.