Daf-2

Concept

A gene mutation in C. elegans, an analog of the IGF-1 receptor, shown to extend lifespan, a foundational discovery in aging.

Mentioned in 4 videos

Videos Mentioning Daf-2

#41–Jake Kushner, M.D.: How to thrive with T1D and the valuable insights that can benefit anyone

#41–Jake Kushner, M.D.: How to thrive with T1D and the valuable insights that can benefit anyone

Peter Attia MD

A gene in C. elegans associated with insulin-like growth factor signaling, whose modulation by Cynthia Kenyon was shown to dramatically extend lifespan in worms.

#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it

#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it

Peter Attia MD

A gene discovered in Cynthia Kenyon's screen, associated with the IGF-1 receptor signaling pathway, manipulated to extend lifespan in C. elegans.

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP

Peter Attia MD

A gene mutation in C. elegans, an analog of the IGF-1 receptor, shown to extend lifespan, a foundational discovery in aging.

#10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — living longer, healthier & turning back the clock

#10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — living longer, healthier & turning back the clock

Peter Attia MD

A gene in C. elegans known to extend lifespan when mutated, part of the insulin/IGF-1 signaling pathway.