Daf-16
Concept
A gene mutation in C. elegans, an analog of FoxO3a/3b, which blocks the lifespan-extending effect of Daf-2 mutations when combined, indicating interaction.
Mentioned in 2 videos
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Videos Mentioning Daf-16
#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it
Peter Attia MD
A gene discovered in Cynthia Kenyon's screen, a transcription factor associated with the IGF-1 receptor signaling pathway, manipulated to extend lifespan in C. elegans.
#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP
Peter Attia MD
A gene mutation in C. elegans, an analog of FoxO3a/3b, which blocks the lifespan-extending effect of Daf-2 mutations when combined, indicating interaction.