Vitamin C
Used judiciously for immune support, especially during travel or high stress; high doses (e.g., 1g) can help prevent respiratory infections without significantly blunting long-term adaptations if timed correctly.
Common Themes
Videos Mentioning Vitamin C
198 - Eye health—everything you need to know | Steven Dell, M.D.
Peter Attia MD
Deficiency is associated with elevated cataract risk, but supranormal supplementation has not been conclusively shown to prevent cataract formation.
Dr. Andy Galpin: The Optimal Diet, Supplement, & Recovery Protocol for Peak Performance
FoundMyFitness
Used judiciously for immune support, especially during travel or high stress; high doses (e.g., 1g) can help prevent respiratory infections without significantly blunting long-term adaptations if timed correctly.
Chris Mason: Space Travel, Colonization, and Long-Term Survival in Space | Lex Fridman Podcast #283
Lex Fridman
An essential nutrient that humans no longer produce endogenously but other animals like dogs and strepserrhine primates still can, due to the presence of the GULO pseudogene.
Developing a Rational Approach to Supplementation for Health & Performance | Huberman Lab Podcast
Andrew Huberman
A water-soluble vitamin that is often excreted when ingested in high levels, leading some to believe vitamin supplements are ineffective.
Responders, Non-Responders, and Fish Oil (Episode 61)
Stronger By Science
An antioxidant that, when used at high doses, may blunt training adaptations, similar to NSAIDs. Lower doses can enhance nitric oxide bioavailability.
Breakfast, Glycine, Muscle Knots, and Trigger Points (Episode 48)
Stronger By Science
A necessary co-factor for collagen synthesis, often recommended to be taken with collagen or gelatin supplements, though typically sufficient in a standard Western diet.
Betaine, Sodium Bicarbonate, and Evaluating New Research as it Develops (Episode 45)
Stronger By Science
A well-known antioxidant; high-dose supplementation showed small reductions in oxidative stress and inflammation markers in a meta-analysis, but did not translate to significant improvements in soreness or strength recovery, making it not recommended as a primary recovery aid for healthy individuals.
#13 – Brett Kotlus, M.D.: How to look younger while we live longer
Peter Attia MD
A powerful antioxidant and cofactor for collagen synthesis, recommended for topical application (preferably with Vitamin E) to protect against UV damage and reverse existing sun damage.
Doping, Collagen, Goals, and Hyperplasia (Episode 33)
Stronger By Science
A vitamin crucial for collagen synthesis; insufficient intake leads to scurvy.
Year in Review, Effective Reps, Antioxidants, Behavior Change, and Mike Tuchscherer (Episode 32)
Stronger By Science
An antioxidant, often taken with Vitamin E, which has been studied for its effects on blunting training adaptations. Recent meta-analyses suggest its negative impact might be overstated, though limited upside is noted for those without high oxidative stress.
E29: Coinbase goes public, direct listings vs. IPOs, unions & more with Bestie Guestie Brad Gerstner
All-In Podcast
Likely discussed as a health or wellness component, possibly related to immune support.
How to Prevent & Treat Colds & Flu
Andrew Huberman
An antioxidant often touted for immune benefits, but recent meta-analyses indicate that very high doses (6-8 grams/day) show only a small and not very robust effect in delaying or shortening colds, with a 2023 meta-analysis being retracted due to data flaws.
Season Finale: Tons of New Meta-Analyses and Q&A Catch-Up (Episode 46)
Stronger By Science
High-dose vitamin C supplementation showed modest effects on oxidative stress and inflammation biomarkers but no significant impact on soreness or strength recovery, with no clear upside for healthy individuals.
How to Improve Skin Health & Appearance
Andrew Huberman
Supplementation of 500-1000 milligrams of Vitamin C can augment the benefits of collagen peptides for skin health.
Effective Reps, Antioxidants, Optimal Training Volume, and Lauren Colenso-Semple (Episode 18)
Stronger By Science
High doses of this antioxidant may decrease hypertrophy or related signaling.
Tools to Reduce & Manage Pain | Dr. Sean Mackey
Andrew Huberman
When taken prophylactically before surgery, it can reduce the likelihood of certain nerve pain conditions post-operatively.