NMN
chemical compound, nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose and is precursor to NAD⁺
Expert discussions of NMN across 16 podcasts.
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Common Themes
Videos Mentioning NMN
AMA #12: Thoughts on Longevity Supplements (Resveratrol, NR, NMN, Etc.) & How to Improve Memory
Andrew Huberman
A precursor to NAD+, discussed as potentially less effective than NR and facing FDA regulatory challenges as a supplement.
Russell Kane: How To Build Confidence & Stay Young | E79
The Diary Of A CEO
A precursor to NAD+, taken by Russell Kane to encourage NAD+ production and help cells copy themselves more accurately, thereby slowing down aging.
The Biology of Slowing & Reversing Aging | Dr. David Sinclair
Andrew Huberman
A precursor to NAD+, which the body uses to make NAD+ in one step. Taking NMN can double NAD+ levels in the blood and improve endurance in old mice. Recommended dosage is 1 gram daily, taken in the morning.
#35 – Nir Barzilai, M.D.: How to tame aging
Peter Attia MD
A precursor to NAD+, taken by Dr. Barzilai, who anecdotally reports improved sleep patterns and deep sleep, sparking hope for its efficacy.
#27 – David Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of aging
Peter Attia MD
A precursor to NAD+ being explored as a supplement for its potential in life extension, with various companies now selling it.
The Science & Practice of Perfecting Your Sleep | Dr. Matt Walker
Andrew Huberman
Supplement mentioned in the context of longevity, but emphasized as less important than fundamental healthy behaviors like sleep and exercise.
AMA #3: supplements, women’s health, patient care, and more (EP.26) | The Peter Attia Drive
Peter Attia MD
Another popular precursor to NAD+, which Attia believes (based on new research) is largely ineffective orally, with uptake primarily in the liver.
"Anti-Aging" Drugs — NAD, metformin, & rapamycin | The Peter Attia Drive Podcast (Ep 207, AMA 35)
Peter Attia MD
A precursor to NAD+ discussed in the context of aging.
Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray
Andrew Huberman
A supplement discussed in the context of NAD+ and its potential effects on energy and longevity, with questions about its efficacy and stability.
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Andrew Huberman
A precursor to NAD+, often taken sublingually. It is observed to accelerate hair and nail growth.
222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D.
Peter Attia MD
Nicotinamide mononucleotide, a molecule mentioned in the context of geroprotection.
204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.
Peter Attia MD
A NAD+ precursor that Dr. Barzilai personally experimented with, noting a temporary improvement in REM sleep but ultimately remaining unconvinced of its overall efficacy due to unclear biology and inconsistent results.
202 - Peter on nutrition, disease prevention, and more — looking back on the last 100 episodes
Peter Attia MD
A common NAD+ precursor that has been shown to increase NAD+ levels, but Peter Attia remains unconvinced of its phenotypic benefits for normal aging individuals.
How Women Can Improve Their Fertility & Hormone Health | Dr. Natalie Crawford
Andrew Huberman
Discussed as potentially advantageous in animal data for unexplained infertility due to its anti-inflammatory properties, but human data is still emerging.
AI Just Compressed 160 Years of Aging Research — Here's What They Found | Dr. David Sinclair
Tom Bilyeu
Nicotinamide mononucleotide, a precursor to NAD+, taken by Dr. Sinclair and his father. He recommends a gram daily and advises checking for purity.
Why You’re Tired, Unmotivated, and Unfocused - Dr. Andrew Huberman (4K)
Chris Williamson
A precursor to NAD+ popularized by David Sinclair. Andrew Huberman takes it sublingually not for longevity, but for faster hair and nail growth and increased morning energy, despite its complex regulatory status with the FDA.