NMN
chemical compound, nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose and is precursor to NAD⁺
Common Themes
Videos Mentioning NMN
AMA #12: Thoughts on Longevity Supplements (Resveratrol, NR, NMN, Etc.) & How to Improve Memory
Andrew Huberman
A precursor to NAD+, discussed as potentially less effective than NR and facing FDA regulatory challenges as a supplement.
Russell Kane: How To Build Confidence & Stay Young | E79
The Diary Of A CEO
A precursor to NAD+, taken by Russell Kane to encourage NAD+ production and help cells copy themselves more accurately, thereby slowing down aging.
The Biology of Slowing & Reversing Aging | Dr. David Sinclair
Andrew Huberman
A precursor to NAD+, which the body uses to make NAD+ in one step. Taking NMN can double NAD+ levels in the blood and improve endurance in old mice. Recommended dosage is 1 gram daily, taken in the morning.
#35 – Nir Barzilai, M.D.: How to tame aging
Peter Attia MD
A precursor to NAD+, taken by Dr. Barzilai, who anecdotally reports improved sleep patterns and deep sleep, sparking hope for its efficacy.
#27 – David Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of aging
Peter Attia MD
A precursor to NAD+ being explored as a supplement for its potential in life extension, with various companies now selling it.
The Science & Practice of Perfecting Your Sleep | Dr. Matt Walker
Andrew Huberman
Supplement mentioned in the context of longevity, but emphasized as less important than fundamental healthy behaviors like sleep and exercise.
AMA #3: supplements, women’s health, patient care, and more (EP.26) | The Peter Attia Drive
Peter Attia MD
Another popular precursor to NAD+, which Attia believes (based on new research) is largely ineffective orally, with uptake primarily in the liver.
"Anti-Aging" Drugs — NAD, metformin, & rapamycin | The Peter Attia Drive Podcast (Ep 207, AMA 35)
Peter Attia MD
A precursor to NAD+ discussed in the context of aging.
Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray
Andrew Huberman
A supplement discussed in the context of NAD+ and its potential effects on energy and longevity, with questions about its efficacy and stability.
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Andrew Huberman
A precursor to NAD+, often taken sublingually. It is observed to accelerate hair and nail growth.
222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D.
Peter Attia MD
Nicotinamide mononucleotide, a molecule mentioned in the context of geroprotection.
204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.
Peter Attia MD
A NAD+ precursor that Dr. Barzilai personally experimented with, noting a temporary improvement in REM sleep but ultimately remaining unconvinced of its overall efficacy due to unclear biology and inconsistent results.
202 - Peter on nutrition, disease prevention, and more — looking back on the last 100 episodes
Peter Attia MD
A common NAD+ precursor that has been shown to increase NAD+ levels, but Peter Attia remains unconvinced of its phenotypic benefits for normal aging individuals.