Heroin

186 - The Opioid Crisis with Patrick Radden Keefe

Peter Attia MD

An illicit opioid drug, whose surge in supply from Mexico after 2010 was linked to the rise of prescription opioid addiction, and which remains a major cause of overdose deaths now.

182 - Psychedelics & Recreational Drugs

Peter Attia MD

A Schedule 1 opiate derivative considered extremely harmful to the user, with high risk of acute and chronic mortality, particularly when laced with fentanyl.

Ant Middleton Opens Up About His Personal Demons, Being "Cancelled" & His Spirituality | E74

The Diary Of A CEO

Used in an analogy with rats to illustrate how a lack of meaning in life can lead to addiction, even when other options are available.

Carl Hart: Heroin, Cocaine, MDMA, Alcohol & the Role of Drugs in Society | Lex Fridman Podcast #233

Lex Fridman

A hard drug discussed by Carl Hart, who argues its effects are heavily influenced by environment and context, challenging the notion that it is inherently destructive.

George Mumford - Mindfulness Coach to Michael Jordan and Kobe Bryant | The Tim Ferriss Show

Tim Ferriss

A drug George Mumford used, leading to track marks on his arms and addiction issues.

#25 – Scott Harrison: transformation, finding meaning, and taking on the global water crisis

Peter Attia MD

The illicit drug Scott Harrison drew the line at, after witnessing its severe, near-fatal consequences.

Matt Walker: Sleep | Lex Fridman Podcast #210

Lex Fridman

An example of a drug of abuse where tolerance and subsequent increased sensitivity after abstinence can lead to overdose, illustrating general drug tolerance mechanisms.

E99: Cheating scandals, Twitter updates, rapid AI advancements, Biden's pardon, Section 230 & more

All-In Podcast

A highly addictive opioid, mentioned to contrast marijuana's classification and to argue for its descheduling.

243 ‒ The fentanyl crisis and why everyone should be paying attention | Anthony Hipolito

Peter Attia MD

One of the primary illicit drugs before the rise of synthetic opioids like fentanyl.

Advil, Aspirin, and Tylenol -- What's the difference?

Sabine Hossenfelder

A highly addictive opioid derived from morphine, illegal and used for recreational purposes, but also with analgesic properties.

Hamilton Morris — Psychedelics, Smart Drugs, and More

Tim Ferriss

An opioid whose addiction has been successfully treated with ibogaine, leading to a loss of desire to use the drug.

Sir Richard Branson Interview | The Tim Ferriss Show (Podcast)

Tim Ferriss

Mentioned in the context of Portugal's successful approach to treating heroin addiction as a health issue.

Dopamine Expert: Doing This Once A Day Fixes Your Dopamine! What Alcohol Is Doing To Your Brain!

The Diary Of A CEO

A substance that, like other potent drugs, significantly decreases dopamine transmission in the brain's reward pathway in addicted individuals, even after two weeks of abstinence.

Health Effects & Risks of Kratom, Opioids & Other Natural Occurring Medicines | Dr. Chris McCurdy

Andrew Huberman

How To Take Back Control Of Your Life From Alcohol, Porn & Social Media | Cal Newport

Cal Newport

Used as an example in 'Chasing the Scream' to illustrate that the substance itself does not guarantee addiction, contrasting medical use with recreational abuse.

209 ‒ Medical mistakes, patient safety, and the RaDonda Vaught case | The Peter Attia Drive Podcast

Peter Attia MD

An illicit opioid that, mixed with fentanyl, contributes to the current opioid death rates in the US.

220 ‒ Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D.

Peter Attia MD

An opioid substance used as a benchmark for addiction potential. Mentioned in the context of Dr. Krapitsky's work on opioid addiction.