dynorphin
An endogenous opioid that acts as a counter-balance to endorphins, potentially involved in thermoregulation and stress response.
Videos Mentioning dynorphin

LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Los Angeles, CA
Andrew Huberman
A molecule released by deliberate heat exposure (like saunas) that acts as an appetite suppressant and can cause agitation, followed by a rebound effect.

Micronutrients for Health & Longevity | Dr. Rhonda Patrick
Andrew Huberman
An endogenous opioid released during sauna use and intense exercise that causes dysphoric feelings but may sensitize mu opioid receptors for a longer-lasting feeling of wellbeing from endorphins.

Roland Griffiths, Ph.D. on Psilocybin, Psychedelic Therapies & Mystical Experiences
FoundMyFitness
An endogenous opioid that acts as a counter-balance to endorphins, potentially involved in thermoregulation and stress response.

Benefits of Sauna & Deliberate Heat Exposure | Huberman Lab Essentials
Andrew Huberman
A type of endorphin that can make us feel worse in response to stressors by binding to the kappa receptor, but paradoxically increases the efficiency of feel-good endorphins over time.