Fenformin

Drug / Medication

An older biguanide drug that had a powerful effect on lactate levels, causing safety concerns and influencing the initial hesitation to bring metformin to the US.

Mentioned in 4 videos

Videos Mentioning Fenformin

#123–Joan Mannick & Nir Barzilai: Rapamycin and metformin—longevity, immune enhancement, & COVID-19

#123–Joan Mannick & Nir Barzilai: Rapamycin and metformin—longevity, immune enhancement, & COVID-19

Peter Attia MD

A cousin of Metformin that was more active against diabetes but associated with lactic acidosis, leading to Metformin's wider use.

#66 – Vamsi Mootha, MD: Aging, T2D, cancer, dementia, Parkinson’s—do all roads lead to mitochondria?

#66 – Vamsi Mootha, MD: Aging, T2D, cancer, dementia, Parkinson’s—do all roads lead to mitochondria?

Peter Attia MD

A more potent drug related to Metformin that can cause fatal lactic acidosis, illustrating the importance of dosage/potency in complex I inhibition.

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.

Peter Attia MD

An early, more potent and toxic form of metformin that caused side effects due to its strong mitochondrial action.

337- Insulin resistance masterclass: The full body impact of metabolic dysfunction, treatment & more

337- Insulin resistance masterclass: The full body impact of metabolic dysfunction, treatment & more

Peter Attia MD

An older biguanide drug that had a powerful effect on lactate levels, causing safety concerns and influencing the initial hesitation to bring metformin to the US.