STRENGTH Trial

Study / Research

Another large trial of high-dose omega-3s (predominantly EPA with DHA) that, when compared to a corn oil placebo, showed essentially no cardiovascular benefit, contrasting with REDUCE-IT.

Mentioned in 4 videos

Videos Mentioning STRENGTH Trial

#134 - James O’Keefe, M.D.: Preventing cardiovascular disease and the risk of too much exercise

#134 - James O’Keefe, M.D.: Preventing cardiovascular disease and the risk of too much exercise

Peter Attia MD

A trial that investigated combined EPA and DHA, but was halted early, leaving questions about the optimal form of omega-3.

#147-Hussein Yassine, M.D.: Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s

#147-Hussein Yassine, M.D.: Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s

Peter Attia MD

Another large trial of high-dose omega-3s (predominantly EPA with DHA) that, when compared to a corn oil placebo, showed essentially no cardiovascular benefit, contrasting with REDUCE-IT.

#83 – Bill Harris, Ph.D.: Omega-3 fatty acids

#83 – Bill Harris, Ph.D.: Omega-3 fatty acids

Peter Attia MD

A large ongoing clinical trial (13,000 patients) testing 4 grams total of EPA plus DHA (Epanova, as free fatty acids) with similar inclusion criteria to REDUCE-IT, expected to finish in about a year and be released at American Heart in 2020.

The Optimal Omega-3 Protocol for Heart, Brain, & Longevity

The Optimal Omega-3 Protocol for Heart, Brain, & Longevity

FoundMyFitness

A trial using 4 grams of EPA and DHA in free fatty acid form (Epanova) that was ended early due to not showing positive results, possibly due to gut irritation from the free fatty acid form.