FOXO3
A gene that acts as a master regulator for many other genes involved in stress resistance, DNA repair, cell death, antioxidant activity, autophagy, and stem cell function. Variations in this gene have been associated with exceptional human longevity.
Videos Mentioning FOXO3

Use of Sauna and Cold to Increase Net Resilience, Mitochondrial Biogenesis, Mood and Longevity
FoundMyFitness
A gene that acts as a master regulator for many other genes involved in stress resistance, DNA repair, cell death, antioxidant activity, autophagy, and stem cell function. Variations in this gene have been associated with exceptional human longevity.

#02 – Rhonda Patrick, Ph.D.: paradox of IGF-1, ketogenic diets and genetics, benefits of sauna, NAD+
Peter Attia MD
A transcription factor in humans, homologous to daf-16 in C. elegans, that regulates genes involved in DNA repair, autophagy, stem cell function, and antioxidant pathways.

Valter Longo, Ph.D. on Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis
FoundMyFitness
A gene/pathway that is a master regulator of stress response, stem cell production, and autophagy, conserved in humans and linked to longevity.