IGF-1

#163 - Layne Norton, Ph.D.: Building muscle, losing fat, and the importance of resistance training

Peter Attia MD

Insulin-like Growth Factor 1. Systemic IGF-1, primarily produced by the liver in response to growth hormone, is not anabolic to skeletal muscle, but autocrine (localized) IGF-1, also known as mechano growth factor, is highly anabolic.

The Science of Healthy Hair, Hair Loss and How to Regrow Hair

Andrew Huberman

Insulin-like Growth Factor 1, a growth factor produced by the liver that acts as a strong accelerator of hair growth by extending the anagen phase. Its activity is influenced by insulin sensitivity.

#35 – Nir Barzilai, M.D.: How to tame aging

Peter Attia MD

Insulin-like Growth Factor 1, a hormone discussed in relation to longevity, growth hormone, and centenarian data, with complex and often contradictory epidemiological findings.

252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting

Peter Attia MD

A growth factor discussed in the context of longevity and protein intake. While excessive levels in the context of a tumor can be problematic, it is important for muscle repair and neurogenesis.

How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Andrew Huberman

Insulin-like Growth Factor 1, a hormone whose levels are sequentially increased by growth hormone, with a much longer half-life.

How to Secure Financial Freedom and Maximize Productivity | The Tim Ferriss Show (Podcast)

Tim Ferriss

A hormone discussed as a health marker to monitor.

How to Control Your Metabolism by Thyroid & Growth Hormone

Andrew Huberman

A hormone released by the liver in response to growth hormone, responsible for improved memory and cognition after exercise, although not linked to neurogenesis in humans.

#02 – Rhonda Patrick, Ph.D.: paradox of IGF-1, ketogenic diets and genetics, benefits of sauna, NAD+

Peter Attia MD

A hormone central to discussions on growth, aging, and longevity. The speakers discuss the paradox of maintaining optimal levels, considering its roles in both growth/repair and potential cancer risk.

Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Andrew Huberman

Insulin-like Growth Factor 1, mediated by growth hormone, plays a role in growth, development, and body composition.

Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation

FoundMyFitness

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray

Andrew Huberman

A factor discussed in relation to growth hormone and its potential impact on vitality versus lifespan.

Valter Longo, Ph.D. on Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis

FoundMyFitness

Insulin-like Growth Factor 1, a growth signaling pathway that plays a role in muscle growth, repair, and brain cell generation, but also linked to cancer promotion when elevated.

Red Meat, Deloads, and Pain with Dr. Michael Ray (Episode 22)

Stronger By Science

Hormone that promotes cell growth and turnover; desired by bodybuilders but often aimed for lower levels by longevity enthusiasts due to its association with aging.

Benefits & Risks of Peptide Therapeutics for Physical & Mental Health

Andrew Huberman

Insulin-like Growth Factor 1, produced by the liver in response to growth hormone, with effects similar to growth hormone.

205 - Energy balance, nutrition, & building muscle | Layne Norton, Ph.D. (Pt.2)

Peter Attia MD

A hormone similar in molecular structure to insulin, important for growth and cell metabolism. Its elevated levels in healthy, resistance-trained individuals are distinguished from chronically high levels associated with poor lifestyle.

Dr. Peter Attia — Interview on Life-Extension, Ultra-Endurance, and More

Tim Ferriss

A hormone similar in molecular structure to insulin that plays a role in aging and cancer, with higher levels potentially problematic; discussed in the context of growth hormone use.

The Science of How to Optimize Testosterone & Estrogen

Andrew Huberman

A hormone in the growth hormone pathway, supposedly high in deer antler material.

Dr. Dominic D'Agostino on Fasting, Ketosis, and The End of Cancer

Tim Ferriss

A growth factor that can be increased by high doses of testosterone and is generally associated with global systemic anabolic effects.