Sucralose

Glucose Goddess: The 10 Glucose Hacks!

The Diary Of A CEO

Artificial sweetener mentioned alongside aspartame as having potential issues; discussed in context of sweeteners.

The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Andrew Huberman

An artificial sweetener that may have small effects on the body but is not comparable to sugary sodas in terms of detrimental impact.

#87—Rick Johnson, MD: Fructose—the common link in hypertension, insulin resistance, T2D, & obesity?

Peter Attia MD

An artificial sweetener, mentioned in the context of safety debates similar to aspartame.

Beta-Alanine, Training Frequency, and Strength for Hypertrophy (Episode 59)

Stronger By Science

A non-nutritive sweetener (brand name Splenda) for which only one study was included in the meta-analysis, but that study showed the largest positive effect size on body weight.

Nutrients For Brain Health & Performance | Huberman Lab Podcast #42

Andrew Huberman

An artificial sweetener whose short-term consumption with carbohydrates was shown to impair neural and metabolic sensitivity to sugar in humans.

Effects of Fasting & Time Restricted Eating on Fat Loss & Health | Huberman Lab Podcast #41

Andrew Huberman

An artificial sweetener that can cause transient increases and decreases in blood glucose, potentially increasing hunger. When consumed in excess, it may have detrimental effects on the gut microbiome.

The Science of Eating for Health, Fat Loss & Lean Muscle | Dr. Layne Norton

Andrew Huberman

An artificial sweetener that showed metabolic effects in a recent two-week human study, but its long-term effects and safety (especially for health outcomes) are still being investigated.

E93: Twitter whistleblower, cloud security vulnerabilities, student debt forgiveness & more

All-In Podcast

An artificial sweetener that, along with saccharin, was found to adversely affect blood glucose control and alter the gut microbiome.

Controlling Sugar Cravings & Metabolism with Science-Based Tools | Huberman Lab Podcast #64

Andrew Huberman

An artificial sweetener that, at high doses in animal studies, has been shown to disrupt the gut microbiome.

Using Salt to Optimize Mental & Physical Performance | Huberman Lab

Andrew Huberman

An artificial sweetener that neuropod cells in the gut can distinguish from caloric sugars. Also mentioned as an additive in processed foods to drive cravings.

How to Enhance Your Gut Microbiome for Brain & Overall Health

Andrew Huberman

An artificial sweetener shown in mouse models to disrupt the gut microbiome, though human data are inconclusive.

How Foods and Nutrients Control Our Moods

Andrew Huberman

A common artificial sweetener mentioned as being distinct from saccharin regarding gut microbiome effects.

Aspartame: The Surprisingly Interesting Science and History (Episode 116)

Stronger By Science

Gut Health with Dr. Gabrielle Fundaro (Episode 40)

Stronger By Science

An artificial sweetener for which human data is notably lacking, though it's molecular similarity to sucrose warrants further investigation.

Q&A: Training frequency, reducing caloric intake on rest days, and isometric training (Episode 39)

Stronger By Science

An artificial sweetener, mentioned to highlight that different artificial sweeteners are distinct compounds and shouldn't be generalized.

Metabolic Rate, Artificial Sweeteners, Electromyography, and Non-Failure Training (Episode 35)

Stronger By Science

An artificial sweetener that tastes good and has shown no meaningful effect on glycemic control or the gut microbiome in recent studies, even at high doses.

Glycogen Loading, Lower Back Pain, PowerBuilding, and Physical Culture with Ben Pollack (Episode 28)

Stronger By Science

An artificial sweetener mentioned in the context of sports nutrition research and its potential effects on the gut microbiome.

Journal Club with Dr. Peter Attia | Effects of Light & Dark on Mental Health & Treatments for Cancer

Andrew Huberman

An artificial sweetener that, in studies, has been linked to an insulin response and potential pre-diabetic conditions in kids, leading to study cessation.