mTOR pathway
A key anabolic signaling pathway for muscle protein synthesis, which appears to be affected by omega-3s, potentially indirectly through enhanced amino acid response.
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Videos Mentioning mTOR pathway
175 - The biology of aging, rapamycin, and other interventions that target the aging process
Peter Attia MD
A fundamental cellular pathway, a target of Rapamycin, which plays a crucial role in regulating cell division and cell cycle, and is central to discussions on aging biology and interventions.
#114 – Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies
Peter Attia MD
A metabolic pathway primarily sensing amino acids, whose downregulation signals nutrient scarcity and triggers autophagy.
The Biology of Slowing & Reversing Aging | Dr. David Sinclair
Andrew Huberman
A cellular pathway that senses protein and amino acid intake; downregulating mTOR during fasting is hugely beneficial for longevity.
The Science of Eating for Health, Fat Loss & Lean Muscle | Dr. Layne Norton
Andrew Huberman
A signaling pathway stimulated by leucine that increases muscle protein synthesis. Its overstimulation is sometimes erroneously linked to early death.
BMI, Plant Based Protein, Stretching, and Mouthguards
Stronger By Science
A theoretical pathway stimulated by phosphatidic acid to facilitate hypertrophy.
Healthy Eating & Eating Disorders - Anorexia, Bulimia, Binging
Andrew Huberman
Mammalian target of Rapamycin, a pathway involving cell growth and muscle protein synthesis, influenced by amino acids like leucine.
Controlling Sugar Cravings & Metabolism with Science-Based Tools | Huberman Lab Podcast #64
Andrew Huberman
A signaling pathway involved in cell growth and metabolism, which is reduced by substances like Berberine as part of longevity strategies.
Effective Reps, Antioxidants, Optimal Training Volume, and Lauren Colenso-Semple (Episode 18)
Stronger By Science
A physiological pathway activated by TRPCV1, which initiates muscle protein synthesis and hypertrophy.
222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D.
Peter Attia MD
A central metabolic pathway that plays a significant role in aging and muscle synthesis, often inhibited by interventions like Rapamycin or caloric restriction.
Outlive: The Science and Art of Longevity — Dr. Peter Attia
Tim Ferriss
The mechanistic target of rapamycin pathway, stimulated by amino acids like leucine, is crucial for promoting muscle growth. Acute stimulation is desired, but chronic stimulation is generally avoided.
Chris McGlory, PhD, on the Anabolic Potential of Omega-3 Fatty Acids
FoundMyFitness
A key anabolic signaling pathway for muscle protein synthesis, which appears to be affected by omega-3s, potentially indirectly through enhanced amino acid response.
Q&A: High Protein Diets, Hardgainers, Exercise Variety, and Bone Adaptations (Episode 29)
Stronger By Science
An anabolic signaling pathway that tends to plateau in muscle protein synthesis after a certain volume of resistance exercise in mice studies, but not necessarily decrease.
Red Meat, Deloads, and Pain with Dr. Michael Ray (Episode 22)
Stronger By Science
Signaling pathway associated with cell growth, including muscle cell growth, which is desirable for building muscle but often targeted for reduction by longevity researchers.