TAME study
An upcoming study that will attempt to answer the question of Metformin's geroprotective effects in humans by studying disease onset in susceptible but otherwise healthy individuals.
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Videos Mentioning TAME study

#123–Joan Mannick & Nir Barzilai: Rapamycin and metformin—longevity, immune enhancement, & COVID-19
Peter Attia MD
A phase 3 clinical trial led by Nir Barzilai, aiming to prove that Metformin can prevent age-related diseases and extend healthy lifespan, with a budget of 78 million dollars and 3,000 subjects.

#103 – Looking back on the first 99 episodes: Strong Convictions, Loosely Held
Peter Attia MD
A study discussed in relation to Metformin's potential to extend life by delaying the onset of chronic disease, particularly in individuals without diabetes.

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.
Peter Attia MD
A groundbreaking clinical trial designed to test metformin's efficacy as a geroprotective agent in non-diabetic elderly individuals, with a primary outcome focused on a cluster of age-related diseases and mortality.

300-Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, & more
Peter Attia MD
An upcoming study that will attempt to answer the question of Metformin's geroprotective effects in humans by studying disease onset in susceptible but otherwise healthy individuals.