Memantine
Drug / Medication
An NMDA receptor blocker used to treat Alzheimer's disease, but noted to have no antidepressant effects, contrasting with ketamine's action.
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Videos Mentioning Memantine

Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast
Andrew Huberman
An NMDA receptor blocker used to treat Alzheimer's disease, but noted to have no antidepressant effects, contrasting with ketamine's action.

#38–Francisco Gonzalez-Lima, Ph.D.: Alzheimer’s disease & the vascular hypothesis
Peter Attia MD
A drug approved for moderate to severe Alzheimer's, which prevents excitotoxicity but is considered counterproductive as it rescues functionally incompetent cells.