Medroxyprogesterone Acetate
A synthetic progestin commonly used with estrogen in HRT (CEE + MPA) for women with a uterus. It was a key component tested in the WHI and implicated in increased breast cancer risk in that arm.
Videos Mentioning Medroxyprogesterone Acetate

#42–Avrum Bluming, M.D. and Carol Tavris, Ph.D.: A compelling case for hormone replacement therapy
Peter Attia MD
A synthetic progestin used in the Women's Health Initiative because it was the most widely prescribed progestin at the time. Its role in breast cancer risk is debated.

How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried
Andrew Huberman
A synthetic progestin used in the Women's Health Initiative, considered by Dr. Gottfried to be dangerous and associated with a greater risk of breast cancer.

253 ‒ Hormone replacement therapy and the Women’s Health Initiative: re-examining the results
Peter Attia MD
A synthetic progestin commonly used with estrogen in HRT (CEE + MPA) for women with a uterus. It was a key component tested in the WHI and implicated in increased breast cancer risk in that arm.