SIRT1
Concept
protein-coding gene in the species Homo sapiens
Mentioned in 4 videos
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Videos Mentioning SIRT1
How To Boost NAD Levels To Fight Inflammation, Improve Recovery, and Slow Aging
FoundMyFitness
A 'longevity gene' that resveratrol and tereselbeane were thought to activate, but evidence for this is questioned.
The Biology of Slowing & Reversing Aging | Dr. David Sinclair
Andrew Huberman
A specific sirtuin gene that is activated by low insulin and insulin-like growth factor levels, crucial for longevity.
#66 – Vamsi Mootha, MD: Aging, T2D, cancer, dementia, Parkinson’s—do all roads lead to mitochondria?
Peter Attia MD
A transcriptional regulator that utilizes NAD+ as a cofactor, upstream of PTC1 alpha, playing a role in mitochondrial biogenesis.
David Sinclair: Extending the Human Lifespan Beyond 100 Years | Lex Fridman Podcast #189
Lex Fridman
A sirtuin gene related to Sir2, which when manipulated in animal brains, led to extended lifespan, highlighting the brain's central role in longevity.