CYP1A2 Gene
A gene encoding liver enzymes responsible for caffeine metabolism, variations in which explain differences in individual caffeine sensitivity and half-life.
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Videos Mentioning CYP1A2 Gene
Matt Walker: Sleep | Lex Fridman Podcast #210
Lex Fridman
A specific gene variant that determines an individual's speed of caffeine clearance, explaining differences in caffeine sensitivity.
Dr. Matt Walker: Protocols to Improve Your Sleep | Huberman Lab Guest Series
Andrew Huberman
A gene encoding liver enzymes responsible for caffeine metabolism, variations in which explain differences in individual caffeine sensitivity and half-life.
Caffeine and Health, Sex-Based Caffeine Differences, and IPF World Champion Natalie Hanson (Ep 6)
Stronger By Science
A specific p450 enzyme gene that may influence individual responses to caffeine, including long-term health outcomes and performance effects, although replication of associated findings is mixed.