Caloric Restriction
An intervention consistently shown to extend life in laboratory animals, often involving the downregulation of mTOR.
Common Themes
Videos Mentioning Caloric Restriction
Journal Club with Dr. Peter Attia | Metformin for Longevity & The Power of Belief Effects
Andrew Huberman
A dietary regimen involving a consistent reduction in calorie intake, explored for its potential to extend lifespan but often difficult to sustain.
#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP
Peter Attia MD
A dietary intervention known to extend lifespan across many species, serving as early proof that aging is malleable, though it typically needs to be initiated early in life.
"Anti-Aging" Drugs — NAD, metformin, & rapamycin | The Peter Attia Drive Podcast (Ep 207, AMA 35)
Peter Attia MD
An intervention studied for its effects on aging, used as an example for biomarker assessment.
369 ‒ Rethinking protein needs for muscle and longevity, and the benefits of creatine & sauna use
Peter Attia MD
An intervention consistently shown to extend life in laboratory animals, often involving the downregulation of mTOR.
222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D.
Peter Attia MD
A dietary intervention involving significant reduction in calorie intake, shown to reproducibly improve lifespan and healthspan in laboratory animals.
Dr. Peter Attia — Interview on Life-Extension, Ultra-Endurance, and More
Tim Ferriss
An anti-aging strategy that, in animal models, appears to increase longevity by delaying metabolic diseases, raising questions about whether the effect comes from caloric reduction or specific macronutrient reduction.