Amyloid Precursor Protein

Concept

A protein located in the cell membrane that, when cholesterol balance is disrupted, can be cleaved by beta and gamma secretases to produce injurious amyloid-beta 42, a hallmark of Alzheimer's disease.

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Videos Mentioning Amyloid Precursor Protein

395 – Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer’s disease, & more

395 – Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer’s disease, & more

Peter Attia MD

A protein located in the cell membrane that, when cholesterol balance is disrupted, can be cleaved by beta and gamma secretases to produce injurious amyloid-beta 42, a hallmark of Alzheimer's disease.