LDL Receptor

Concept

Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein into the cell via endocytosis.

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Videos Mentioning LDL Receptor

#23–Tom Dayspring Part IV of V: statins, Zetia, PCSK9 inhibitors, niacin, cholesterol & the brain

#23–Tom Dayspring Part IV of V: statins, Zetia, PCSK9 inhibitors, niacin, cholesterol & the brain

Peter Attia MD

A key protein discovered by Brown and Goldstein, responsible for clearing LDL particles from the blood. Drugs that increase its expression or half-life are effective in lowering atherogenic lipoproteins.

#20 – Tom Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology

#20 – Tom Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology

Peter Attia MD

A type of receptor on cell membranes that influences cellular processes, whose expression can be influenced by the composition of the lipid membrane.

255-Latest therapeutics in CVD, APOE’s role in Alzheimer’s disease, familial hypercholesterolemia

255-Latest therapeutics in CVD, APOE’s role in Alzheimer’s disease, familial hypercholesterolemia

Peter Attia MD

A protein on the liver cell surface that binds and internalizes LDL particles.

334 - Cardiovascular disease, the number one killer: development, biomarkers, apoB, and more

334 - Cardiovascular disease, the number one killer: development, biomarkers, apoB, and more

Peter Attia MD

A protein on the surface of liver cells that binds to ApoB-containing lipoproteins (like LDL) to clear them from plasma, crucial for maintaining healthy lipid levels.