Bempedoic Acid

#129 - Tom Dayspring, M.D.: The latest insights into cardiovascular disease and lipidology

Peter Attia MD

A recently introduced drug that inhibits cholesterol synthesis by targeting ATP citrate lyase, offering an additional ApoB-lowering option, especially for statin-intolerant patients.

Insights from Sam Harris, Dr. Peter Attia, Ramit Sethi, and Elizabeth Gilbert | The Tim Ferriss Show

Tim Ferriss

A drug used to lower cholesterol when statins are not tolerated or insufficient, particularly for hypersynthesizers.

Exercise, Nutrition, Hormones for Vitality & Longevity | Dr. Peter Attia

Andrew Huberman

A drug that blocks cholesterol synthesis specifically in the liver, offering a similar but less potent mechanism than statins with fewer side effects.

Dr. Peter Attia on Mastering Longevity – Insights on Cancer Prevention, Heart Disease, and Aging

FoundMyFitness

A prodrug that inhibits cholesterol synthesis specifically in the liver, leading to lower ApoB and LDL cholesterol without the side effects of statins, but it is currently expensive.

334 - Cardiovascular disease, the number one killer: development, biomarkers, apoB, and more

Peter Attia MD

255-Latest therapeutics in CVD, APOE’s role in Alzheimer’s disease, familial hypercholesterolemia

Peter Attia MD

Another lipid-lowering drug with a good safety profile, comparable to newer agents.

2024 New Year’s Resolutions, AI Upheavel, & Much More! | The Random Show (4K)

Tim Ferriss

A newer component of Nexletol, combined with ezetimibe to manage lipid profiles.

Supplements for Longevity & Their Efficacy | Dr. Peter Attia

Andrew Huberman

A medication taken by Peter Attia to directly impact cardiovascular disease processes.

230 ‒ Cardiovascular disease in women: prevention, risk factors, lipids, and more

Peter Attia MD

An oral drug that blocks cholesterol synthesis (Upstream of HMG CoA reductase), lowering LDL by ~18% (monotherapy) or ~36% (with ezetimibe). It does not cause muscle symptoms or increase glucose, making it a good option for statin-intolerant patients.