Sorafenib
A drug for liver cancer that could not be treated by surgery. While it extended median survival by about three months in clinical trials, real-world data showed little to no benefit, and it only provided a 50% survival duration compared to the placebo arm in trials.
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Videos Mentioning Sorafenib

#133 - Vinay Prasad, M.D., M.P.H: Hallmarks of successful cancer policy
Peter Attia MD
A drug for liver cancer that could not be treated by surgery. While it extended median survival by about three months in clinical trials, real-world data showed little to no benefit, and it only provided a 50% survival duration compared to the placebo arm in trials.

409 ‒ Inside modern drug development: the science, economics, and regulatory hurdles
Peter Attia MD
A multikinase inhibitor used to treat renal cell carcinoma and hepatocellular carcinoma, which causes skin cancers as a side effect, illustrating a cancer protective pathway.