Sildenafil
A phosphodiesterase-5 inhibitor that blocks the enzyme phosphodiesterase, increasing cyclic GMP to maintain erections. It was originally developed as a blood pressure medication.
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Videos Mentioning Sildenafil
Improving Male Sexual Health, Function & Fertility | Dr. Michael Eisenberg
Andrew Huberman
An oral phosphodiesterase inhibitor, a first-line treatment for erectile dysfunction, effective for 60-70% of men. Also known by its brand name, Viagra.
#118 – Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging
Peter Attia MD
Another PDE5 inhibitor, mentioned in contrast to Cialis for its shorter half-life.
260 ‒ Men’s Sexual Health: why it matters, what can go wrong, and how to fix it
Peter Attia MD
A phosphodiesterase-5 inhibitor that blocks the enzyme phosphodiesterase, increasing cyclic GMP to maintain erections. It was originally developed as a blood pressure medication.
How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett
Andrew Huberman
A phosphodiesterase inhibitor with a shorter half-life than tadalafil, primarily used for erectile dysfunction. May also increase eyebrow hair growth by improving blood flow and can potentially alter vision.
199 - Running, overcoming challenges, and finding success | Ryan Hall
Peter Attia MD
A medication explored by Peter as a potential performance-enhancing drug for muscular endurance, but found to cause lightheadedness.
#500! KevKev TimTim TalkTalk on Dragon Slaying, Lessons Learned, Viagra, and Assorted Nonsense
Tim Ferriss
The active ingredient in Viagra, mentioned as a phosphodiesterase inhibitor.