Tangier disease

Condition / Disease

A rare human genetic disorder caused by a lack of ABC A1, resulting in virtually undetectable HDL and accumulation of cholesterol in macrophages throughout the body, leading to enlarged tonsils, spleen, and neurological issues.

Mentioned in 1 video

Videos Mentioning Tangier disease

240 ‒ The confusion around HDL and its link to cardiovascular disease | Dan Rader, M.D.

240 ‒ The confusion around HDL and its link to cardiovascular disease | Dan Rader, M.D.

Peter Attia MD

A rare human genetic disorder caused by a lack of ABC A1, resulting in virtually undetectable HDL and accumulation of cholesterol in macrophages throughout the body, leading to enlarged tonsils, spleen, and neurological issues.