Phospholipase A2

ConceptMentioned in 1 video

A specific enzyme strongly upregulated and activated in APOE4 Alzheimer's disease brains, which extracts fatty acids from phospholipid membranes, potentially to generate ATP, with side effects of neural inflammation and oxidative stress.

Videos Mentioning Phospholipase A2

#147-Hussein Yassine, M.D.: Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s

#147-Hussein Yassine, M.D.: Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s

Peter Attia MD

A specific enzyme strongly upregulated and activated in APOE4 Alzheimer's disease brains, which extracts fatty acids from phospholipid membranes, potentially to generate ATP, with side effects of neural inflammation and oxidative stress.