Mitochondrial glycerol phosphate dehydrogenase

Concept

An enzyme in the mitochondria that Metformin is proposed to indirectly inhibit, leading to changes in NADH and NAD+ levels and substrate-dependent inhibition of gluconeogenesis.

Mentioned in 1 video

Videos Mentioning Mitochondrial glycerol phosphate dehydrogenase

#140 - Gerald Shulman, MD, PhD: Insulin resistance—molecular mechanisms and clinical implications

#140 - Gerald Shulman, MD, PhD: Insulin resistance—molecular mechanisms and clinical implications

Peter Attia MD

An enzyme in the mitochondria that Metformin is proposed to indirectly inhibit, leading to changes in NADH and NAD+ levels and substrate-dependent inhibition of gluconeogenesis.