GLP-1 agonists

381‒Alzheimer’s disease in women: how hormonal transitions impact the brain, new therapies, & more

Peter Attia MD

Drug class discussed as potential brain health modulators; evidence discussed is preliminary.

How to Quiet the Ruminative Mind and Avoid The Traps of Self-Help — Tim Ferriss

Tim Ferriss

A class of drugs with observed amazing results in literature, but with unknown long-term effects.

378 ‒ Women’s health & performance: how training, nutrition, & hormones interact across life stages

Peter Attia MD

How To Build A Truly Abundant Future

Y Combinator

DOGE unveils a roadmap, Unlocking GDP Growth, WW3 escalation, Fat cell memory

All-In Podcast

Drugs like Ozempic and Wegovy, which are effective for weight loss but often lead to weight regain when discontinued, are discussed in the context of epigenetic memory in fat cells.

Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Andrew Huberman

A class of glucagon-like peptide analogs, including popular drugs like Ozempic and Mounjaro, primarily used for glucose control in type 2 diabetics, with weight loss as a significant side effect.

Tools for Nutrition & Fitness | Dr. Layne Norton

Andrew Huberman

A class of drugs that mimic glucagon-like peptide-1, a gut hormone that reduces appetite and slows gastrointestinal motility. These drugs have a longer half-life than natural GLP-1, making them effective for weight loss. Viewed as a net positive for public health despite potential side effects and concerns about lean mass loss.

252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting

Peter Attia MD

A class of drugs (e.g., semaglutide, tirzepatide) effective for weight loss by squashing appetite. Discussed with reservations about liberal use, stressing the importance of high protein intake to prevent muscle loss.

Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent [AMA 45 sneak peek]

Peter Attia MD

A class of drugs that are the primary topic of discussion, known for their effects on blood glucose and weight loss.