Klotho
Concept
A protein that plays a significant role in brain health and cognition. Its levels decline with age and can be influenced by factors like stress and exercise.
Mentioned in 3 videos
Videos Mentioning Klotho

Klotho: what it is and why it could have breakthrough potential for brain health
Peter Attia MD
A protein that plays a significant role in brain health and cognition. Its levels decline with age and can be influenced by factors like stress and exercise.

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray
Andrew Huberman
A protein discussed as having beneficial effects on multiple organs, with companies trying to move it into human trials.

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.
Peter Attia MD
A gene (or its variants) that showed a U-shaped longevity curve in centenarians, suggesting that while some variants may be detrimental at younger ages, other protective mechanisms or variants render it irrelevant later in life.