CTLA-4
A receptor on T-cells that acts as a 'brake' on the immune system, preventing an overactive response; blocking it is a strategy in immunotherapy to unleash the immune system against cancer.
Videos Mentioning CTLA-4

177 - The development of cancer immunotherapy and its promise for treating advanced cancers
Peter Attia MD
A molecule on T-cell surfaces that acts as an inhibitory brake on immune reactions; targeting it with antibodies (checkpoint inhibitors) can unleash the T-cell activity against cancer.

#32–Siddhartha Mukherjee, M.D., Ph.D.: new frontiers in cancer therapy, medicine, and writing
Peter Attia MD
One of the checkpoint inhibitor targets in immunotherapy, recognized with a Nobel Prize for its role in cancer treatment.

202 - Peter on nutrition, disease prevention, and more — looking back on the last 100 episodes
Peter Attia MD
A checkpoint on immune cells, targeted by checkpoint inhibitor drugs to block the 'brakes' on the immune system, allowing it to better fight cancer.

286‒Journal club with Andrew Huberman: light exposure on mental health & an immunotherapy for cancer
Peter Attia MD
A receptor on T-cells that acts as a 'brake' on the immune system, preventing an overactive response; blocking it is a strategy in immunotherapy to unleash the immune system against cancer.

Journal Club with Dr. Peter Attia | Effects of Light & Dark on Mental Health & Treatments for Cancer
Andrew Huberman
A checkpoint receptor on T-cells that acts as a 'brake' on the immune system, preventing it from overreacting. Blocking it is a strategy for cancer immunotherapy.