Antagonistic Pleiotropy Hypothesis

Concept

A theory of aging that suggests traits beneficial early in life (like high IGF-1 for growth) can become detrimental later in life, driving further age-related decline or disease.

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Videos Mentioning Antagonistic Pleiotropy Hypothesis

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.

Peter Attia MD

A theory of aging that suggests traits beneficial early in life (like high IGF-1 for growth) can become detrimental later in life, driving further age-related decline or disease.