27-hydroxycholesterol

Concept

Another cholesterol metabolite that can cross the blood-brain barrier, and its levels were reduced in CSF in a pilot study of Obicetrapib, indicating target engagement.

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Videos Mentioning 27-hydroxycholesterol

407 ‒ Preventing cardiovascular and Alzheimer’s disease: lowering LDL early, APOE4, and more

407 ‒ Preventing cardiovascular and Alzheimer’s disease: lowering LDL early, APOE4, and more

Peter Attia MD

Another cholesterol metabolite that can cross the blood-brain barrier, and its levels were reduced in CSF in a pilot study of Obicetrapib, indicating target engagement.