Vioxx

Supercharging a New FDA: Marty Makary on Science, Power & Patients

All-In Podcast

A drug that caused significant harm, highlighting the need for post-market surveillance.

186 - The Opioid Crisis with Patrick Radden Keefe

Peter Attia MD

A strong NSAID that 'basically saved' Peter Attia by breaking the cycle of pain, allowing him to avoid narcotics post-surgery.

John Abramson: Big Pharma | Lex Fridman Podcast #263

Lex Fridman

A drug withdrawn from the market in 2004 due to significantly increased risk of heart attacks, strokes, and blood clots, where Merck allegedly omitted crucial data from a New England Journal of Medicine study.

Bret Weinstein on "The Portal" (w/ host Eric Weinstein), Ep. #019 - The Prediction and the DISC.

Eric Weinstein

#87—Rick Johnson, MD: Fructose—the common link in hypertension, insulin resistance, T2D, & obesity?

Peter Attia MD

A pain medication historically associated with increased cardiovascular risk, used as an analogy to describe the flawed clinical trial comparing allopurinol and febuxostat.

#22 – Tom Dayspring Part III of V: reverse cholesterol transport, CETP inhibitors, & apolipoproteins

Peter Attia MD

A selective COX-2 inhibitor that was withdrawn from the market due to cardiovascular risks, discussed as a case study in pharmaceutical risk assessment and regulatory decisions.

Bret Weinstein: Truth, Science, and Censorship in the Time of a Pandemic | Lex Fridman Podcast #194

Lex Fridman

A drug that turned out to cause conspicuous heart damage, cited as an example of errors resulting from using flawed laboratory mice models in pharmaceutical testing that predispose systems to declare toxic compounds safe.

A Contagion of Bad Ideas: A Conversation with Eric Topol (Episode #256)

Sam Harris

A Merck drug that Eric Topol took on, a past event that underscores his independence from or criticism of pharmaceutical companies.

Robert F. Kennedy Jr: CIA, Power, Corruption, War, Freedom, and Meaning | Lex Fridman Podcast #388

Lex Fridman